Ingredient References

We hold ourselves to the highest scientific standards.  

After researching all the Ayurvedic, traditional Chinese, and western literature regarding aging, we selected only the highest quality scientifically-validated ingredients that significantly contribute to product efficacy.  

In the spirit of transparency and a commitment to consumer confidence, we will share some of the research for ingredients in our skincare supplements.

ingredients
STUDIES
Ascorbic Acid - Vitamin C

The effect of ascorbic acid supplementation on some parameters of the human immunological defence system

Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts

Astaxanthin 

Protective effects of astaxanthin on skin: Recent scientific evidence, possible mechanisms, and potential indications

Cosmetic benefits of astaxanthin on human subjects

Choline

Dietary Choline-Enhanced Skin Immune Response of Juvenile Grass Carp Might Be Related to the STAT3 and NF-kB Signaling Pathway (Ctenopharyngodon idella)


The Metabolic Burden of Methyl Donor Deficiency with Focus on the Betaine Homocysteine Methyltransferase Pathway

CoQ10 

Influence of CoQ10 on autonomic nervous activity and energy metabolism during exercise in healthy subjects


Coenzyme Q10--its importance, properties and use in nutrition and cosmetics


The effect of dietary intake of coenzyme Q10 on skin parameters and condition: Results of a randomised, placebo-controlled, double-blind study

Fisetin 

Fisetin is a senotherapeutic that extends health and lifespan

Holy Basil 

Holy basil (Ocimum sanctum Linn.) leaf extract enhances specific cognitive parameters in healthy adult volunteers: A placebo controlled study

Hyaluronic Acid 

Ingested hyaluronan moisturizes dry skin

Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period

Niacinamide 

Niacinamide: A B vitamin that improves aging facial skin appearance


A nonrandomized study of single oral supplementation within the daily tolerable upper level of nicotinamide affects blood nicotinamide and NAD+ levels in healthy subjects


Nature Aging


NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

Milk Thistle

Milk Thistle

Olive Fruit 

Hydroxytyrosol from olive fruits prevents blue-light-induced damage in human keratinocytes and fibroblasts


Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes


Antioxidant Effects of a Hydroxytyrosol-Based Pharmaceutical Formulation on Body Composition, Metabolic State, and Gene Expression: A Randomized Double-Blinded, Placebo-Controlled Crossover Trial

Piperine

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers


Bioavailability enhancers of herbal origin: An overview

Tiger Grass

Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract

Turmeric 

Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence

Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review


Effects of curcumin supplementation on markers of inflammation and oxidative stress among healthy overweight and obese girl adolescents: A randomized placebo-controlled clinical trial


Potential of Curcumin in Skin Disorders

Vitamin D3 

Association of facial skin aging and vitamin D levels in middle-aged white women


Regulation of Phosphate Homeostasis by PTH, Vitamin D, and FGF23


Vitamin D and Intestinal Calcium Absorption

Vitamin E 

Vitamin E in dermatology


Skin bioavailability of dietary vitamin E, carotenoids, polyphenols, vitamin C, zinc and selenium


Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids


Vitamin E: Critical Review of Its Current Use in Cosmetic and Clinical Dermatology

Vitamin K2

The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review


Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging?


The role of menaquinones (vitamin K₂) in human health