Skincare is finally catching up to longevity science. Discover why NAD+ is becoming the molecule to watch in 2026—and how Aramore’s breakthrough formulas support brighter, smoother, and younger-acting skin by working directly with your biology. In collaboration with Aramore Skincare.
(originally published by The Ageist)
Every January comes with predictions, but 2026 will belong to biology-driven skincare. While temporary solutions for dryness, dullness and fine lines serve a purpose, addressing skincare needs at the molecular level is where we can prolong our skin cell health. At the center of this shift is NAD+ (nicotinamide adenine dinucleotide)—a coenzyme found in every cell of our body.
NAD+ is essential for cellular energy and repair. It helps our skin cells function, renew, and recover. The challenge is that NAD+ declines steadily with age, and until recently, there was no scientifically proven way to replenish it topically.
That is what makes Aramore Skincare so compelling. With decades of expertise in stem cell biology, dermatology, chemistry, and medicine, the scientific co-founders think about how skin works—not just how it looks. In bringing NAD+ support directly to the cells where aging begins, Aramore has built solutions that work with the skin’s own biology to support the healthy rate of skin cell production deep within the basal layer, where new cells form.
What NAD+ Is and Why It Matters
The coenzyme NAD+ plays two essential roles inside every cell: fueling cellular energy and supporting DNA repair at the structural level. Boosting this coenzyme helps our skin cells carry out the basic functions that keep them alive and active, which is increasingly important as our cells navigate daily environmental stressors.
When NAD+ production slows, our skin cells turn over less efficiently and our skin’s barrier becomes weaker. Changes in tone, texture, radiance, and firmness become more visible, not because the surface of our skin has changed suddenly, but because the underlying biology is no longer operating at an optimal pace.
Built on decades of research from leaders in skin science at Harvard and MIT, Aramore is the first clinically proven skincare specifically engineered to address NAD+ decline at the cellular level. It is not just another trendy ingredient; it is foundational biology that supports cellular energy and helps slow the major pathways of visible skin aging to promote longer-term skin health.
Why Topical NAD+ Support Is a Breakthrough
For years, researchers understood the importance of NAD+ in maintaining healthy cell function, but there was one major obstacle: NAD+ molecules themselves are too large to penetrate the skin. This meant that even the most advanced topical formulas remained on the surface, addressing dryness or texture without meaningfully influencing the biology beneath.
Reaching the basal layer — where new skin cells form and where aging actually begins — requires a different strategy. Instead of applying NAD+ directly, scientists turned their attention to precursors and specialized delivery systems that could move through the skin barrier and activate NAD+ pathways from within. This is the scientific leap that Harvard and MIT researchers led by Dr. Anna Mandinova helped make possible, opening the door to a new era of solutions capable of supporting cellular energy and renewal at the source.
Aramore turned this breakthrough into the foundation of its skin system: the NAD+ Cell Energizing Treatment. Dr. Mandinova’s skin biology research is now available as a serum designed to stimulate the body’s ability to create more of its own NAD+. By strengthening how skin functions beneath the surface, your existing products will work more effectively on visible concerns around texture, tone, and hydration.
The Next Era of Skin Health
This next era of skin health moves well past traditional beauty products and toward understanding how skin performs at the cellular level. When cells have the energy and support they need, the skin behaves differently—it’s brighter, smoother, stronger-acting, and better able to maintain its own health over time.
NAD+ topical support represents a meaningful shift in skincare, similar to how innovations like GLP-1 therapies, hormone replacement, and stem cell research have reshaped how we think about health at the biological level. Rather than masking symptoms, this type of breakthrough focuses on improving how the body functions from within. Aramore applies that same thinking to skin, translating advanced skin biology into topical formulas that work where cells regenerate. It is a forward-looking approach designed for anyone ready to pair scientific rigor with long-term skin well-being.
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